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Job Category : | Engineer |
Company Name: | Immunai |
Position Name: | Scientist/Senior Scientist, Protein Engineering |
Location : | New York, NY 10014 |
Job Description : | Position – Scientist/Senior Scientist, Protein Engineering Mission Statement Through single-cell biology, computational biology, and artificial intelligence, Immunai is reprogramming the immune system to develop improved drugs and therapeutics. Background Immunai was founded in December 2018. We are a multidisciplinary team of immunologists, genomics technologists, computer scientists, engineers, mathematicians and operators singularly focused on solving an audacious challenge. Backed by some of the leading scientific minds in immunology, oncology, and single cell genomics, we are up for the challenge. Immunai has begun the process of mapping millions of immune cells and their functions in order to build a proprietary data set for clinical immunological data. The immune system mapping will play an important role in boosting R&D efforts in developing targeted therapies for different diseases. The company noted that the immune system consists of trillions of cells that are divided into different cell types that perform different functions. Because of the complexity of the system, it can be difficult to determine how drugs will interact with the immune cells. This increased understanding can be used to boost clinical response to different cellular therapies. Immunai’s mission is to map the immune system with neural networks and transfer learning techniques informed by deep immunology knowledge. We developed the tools and knowhow to help every immuno-oncology and cell therapy researcher excel at their job. This helps increase the speed in which drugs are developed and brought to market by elucidating their mechanisms of action and resistance. Location – For details – www.immunai.com , info@immunai.com Responsibilities Responsible for developing and running in vitro potency assays, mAb binding and neutralization assay Responsible for generation of Fab and Fab’2 from mAb preparation and purification Responsible for the generation of plasmid constructs and the generation and maintenance of tool reagents such as reporter cell lines Responsible for generation of cell lines and recombinant proteins by transient and stable transfection or lentivirus transduction Interface with disease biology teams to coordinate evaluation of candidate therapeutics in in vitro studies Coordinate with in vivo pharmacology team to evaluate PK/PD of candidate therapeutics Develop robust data packages, co-author accompanying reports to support regulatory filing Requirements: |
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